Basic Information

Gene symbol KLRK1 Synonyms CD314, D12S2489E, KLR, NKG2-D, NKG2D Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description killer cell lectin like receptor K1

GTO ID GTC1857
Trial ID NCT03415100
Disease Colorectal Cancer
Altered gene NKG2D
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment NKG2D CAR-NK cells
PhasePhase1
Recruitment statusUnknown
TitlePilot Study of NKG2D-Ligand Targeted CAR-NK Cells in Patients With Metastatic Solid Tumours
Year2018
CountryChina
Company sponsorThe Third Affiliated Hospital of Guangzhou Medical University
Other ID(s)NRC-NK-01
Vector information
Vectorelectroporation
Additional featureIL-2

Clinical Result

Cohort 1
Administration route None
Donor type Allogeneic
Pts 30
Age Adult, Older_Adult
Lymph depletion No

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