Gene symbol | MME | Synonyms | CALLA, CD10, CMT2T, NEP, SCA43, SFE | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3q25.2 | dbXrefs | |
Description | membrane metalloendopeptidase |
Gene symbol | MS4A1 | Synonyms | B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q12.2 | dbXrefs | |
Description | membrane spanning 4-domains A1 |
Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD22 molecule |
GTO ID | GTC1855 |
Trial ID | NCT03407859 |
Disease | B-Cell Acute Lymphoblastic Leukemia |
Altered gene | CD20|CD22|CD10 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD10/CD20/CD22 CAR-T cells |
Phase | Early_Phase1 |
Recruitment status | Unknown |
Title | Sequential Treatment With CD20/CD22/CD10-CART After CD19-CART Treatment Base on MRD in Relapsed/Refractory B-ALL |
Year | 2016 |
Country | China |
Company sponsor | Zhujiang Hospital |
Other ID(s) | 2016-XYNK-002 |
Cohort 1 | |||||||||
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