Basic Information

Gene symbol MME Synonyms CALLA, CD10, CMT2T, NEP, SCA43, SFE Type of gene protein-coding
Description membrane metalloendopeptidase

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC1855
Trial ID NCT03407859
Disease B-Cell Acute Lymphoblastic Leukemia
Altered gene CD20|CD22|CD10
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD10/CD20/CD22 CAR-T cells
PhaseEarly_Phase1
Recruitment statusUnknown
TitleSequential Treatment With CD20/CD22/CD10-CART After CD19-CART Treatment Base on MRD in Relapsed/Refractory B-ALL
Year2016
CountryChina
Company sponsorZhujiang Hospital
Other ID(s)2016-XYNK-002

Clinical Result

Cohort 1
Administration route None
Dosage 1~5E6 cells/kg
Pts 30
Age Adult

Relationship Graph

Overview of Knowledge Graph