Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | MS4A1 | Synonyms | B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q12.2 | dbXrefs | |
Description | membrane spanning 4-domains A1 |
Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD22 molecule |
GTO ID | GTC1852 |
Trial ID | NCT03398967 |
Disease | B-Cell Lymphoma | B-Cell Leukemia |
Altered gene | CD19|CD20|CD22 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD19/CD20/CD22 CAR-T cells |
Phase | Phase1|Phase2 |
Recruitment status | Unknown |
Title | A Feasibility and Safety Study of Universal Dual Specificity CD19 and CD20 or CD22 CAR-T Cell Immunotherapy for Relapsed or Refractory Leukemia and Lymphoma |
Year | 2018 |
Country | China |
Company sponsor | Chinese PLA General Hospital |
Other ID(s) | CHN-PLAGH-BT-026 |
Cohort 1 | |||||||||
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