Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC1852
Trial ID NCT03398967
Disease B-Cell Lymphoma | B-Cell Leukemia
Altered gene CD19|CD20|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD20/CD22 CAR-T cells
PhasePhase1|Phase2
Recruitment statusUnknown
TitleA Feasibility and Safety Study of Universal Dual Specificity CD19 and CD20 or CD22 CAR-T Cell Immunotherapy for Relapsed or Refractory Leukemia and Lymphoma
Year2018
CountryChina
Company sponsorChinese PLA General Hospital
Other ID(s)CHN-PLAGH-BT-026

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Allogeneic
Pts 80
Age Child, Adult, Older_Adult

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