Basic Information

Gene symbol ROR2 Synonyms BDB, BDB1, NTRKR2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description receptor tyrosine kinase like orphan receptor 2

GTO ID GTC1849
Trial ID NCT03393936
Disease Renal Cell Carcinoma
Altered gene ROR2
Therapeutic/Target gene Therapeutic gene
TherapyCAR-T cell
Treatment CCT301-59|CCT301-38
PhasePhase1|Phase2
Recruitment statusActive, Not Recruiting
TitleSafety and Efficacy of CCT301 CAR-T in Adult Subjects With Recurrent or Refractory Stage IV Renal Cell Carcinoma
Year2018
CountryChina
Company sponsorShanghai PerHum Therapeutics Co., Ltd.
Other ID(s)CCT301-mRCC01

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E5 cells/kg, 1E6 cells/kg, 1E7 cells/kg
Donor type Autologous
Pts 66
Age Adult, Older_Adult
Lymph depletion Yes

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