| Gene symbol | APOA1 | Synonyms | AMYLD3, HPALP2, apo(a) | Type of gene | protein-coding |
| Chromosome | 11 | Map location | 11q23.3 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | apolipoprotein A1 | ||||
| GTO ID | GTC1845 |
| Trial ID | NCT03392051 |
| Disease | Cardiovascular System Disease |
| Altered gene | APOA1 |
| Therapeutic/Target gene | Target gene |
| Therapy | ASO |
| Treatment | ISIS 681257|AKCEA-APO(a)-LRx|IONIS-APO(a)-LRx|TQJ230|Pelacarsen |
| Co-treatment | Clopidogrel |
| Phase | Phase1 |
| Recruitment status | Completed |
| Title | Drug-Drug Interaction Study To Evaluate The Effect Of Multiple Doses Of ISIS 681257 40 mg Subcutaneous Injections On The Pharmacokinetics And Pharmacodynamics Of Clopidogrel In Healthy Subjects |
| Year | 2017 |
| Country | Canada |
| Company sponsor | Akcea Therapeutics |
| Other ID(s) | ISIS 681257-CS11 |
| Vector information | |||
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| Cohort1: Clopidogrel | |||||||
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| Cohort2: ISIS 681257_Clopidogrel | |||||||
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