Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC1833
Trial ID NCT03373071
Disease Acute Lymphoblastic Leukemia | Non-Hodgkin's Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
PhasePhase1|Phase2
Recruitment statusActive, Not Recruiting
TitleAnti-CD19 CAR T Cells in Pediatric Patients Affected by Relapsed/Refractory CD19+ ALL and NHL
Year2017
CountryItaly
Company sponsorBambino Gesù Hospital and Research Institute
Other ID(s)CD19-CAR01

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 0.5~3E6 cells/kg
Donor type Autologous
Pts 29
Age Child, Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph