Basic Information

Gene symbol C5 Synonyms C5D, C5a, C5b, CPAMD4, ECLZB Type of gene protein-coding
Description complement C5

GTO ID GTC1828
Trial ID NCT03364153
Disease Stargardt Disease
Altered gene C5
Therapeutic/Target gene Target gene
TherapyAptamer
Treatment Avacincaptad pegol|Zimura;ARC1905
PhasePhase2
Recruitment statusActive, Not Recruiting
TitleA Phase 2b Randomized, Double-masked, Controlled Trial to Establish the Safety and Efficacy of Zimura (Complement C5 Inhibitor) Compared to Sham in Subjects With Autosomal Recessive Stargardt Disease
Year2018
CountryFrance|Germany|Hungary|Israel|Italy|Spain|United Kingdom|United States
Company sponsorIVERIC bio, Inc.
Other ID(s)OPH2005

Clinical Result

Cohort1: avacincaptad pegol
Administration route intravitreal injection
Dosage avacincaptad pegol, monthly, up to 17 Months
Age Adult
Cohort2: Sham
Administration route intravitreal injection
Dosage matching sham, monthly, for up to 17 Months
Age Adult

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