Gene symbol | KIT | Synonyms | C-Kit, CD117, MASTC, PBT, SCFR | Type of gene | protein-coding |
Chromosome | 4 | Map location | 4q12 | dbXrefs | |
Gene perturbation-related omics dataset | PertOrg | ||||
Description | KIT proto-oncogene, receptor tyrosine kinase |
Gene symbol | PROM1 | Synonyms | AC133, CD133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4 | Type of gene | protein-coding |
Chromosome | 4 | Map location | 4p15.32 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | prominin 1 |
Gene symbol | MUC1 | Synonyms | ADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM | Type of gene | protein-coding |
Chromosome | 1 | Map location | 1q22 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | mucin 1, cell surface associated |
GTO ID | GTC1822 |
Trial ID | NCT03356782 |
Disease | Sarcoma | Osteosarcoma | Ewing Sarcoma |
Altered gene | CD133|GD2|MUC1|CD117 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD133/GD2/Muc1/CD117 CAR-T cells |
Generation | 4th |
Phase | Phase1|Phase2 |
Recruitment status | Recruiting |
Title | Safety and Efficacy Evaluation of 4th Generation Safety-engineered CAR T Cells Targeting Sarcomas |
Year | 2017 |
Country | China |
Company sponsor | Shenzhen Geno-Immune Medical Institute |
Other ID(s) | GIMI-IRB-17016 |
Cohort 1 | |||||||||
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