| Gene symbol | CD274 | Synonyms | B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, hPD-L1 | Type of gene | protein-coding |
| Chromosome | 9 | Map location | 9p24.1 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | CD274 molecule | ||||
| GTO ID | GTC1814 |
| Trial ID | NCT03330834 |
| Disease | Lung Cancer |
| Altered gene | PD-L1 |
| Therapeutic/Target gene | Target gene |
| Therapy | CAR-T cell |
| Treatment | PD-L1 CAR-T cells |
| Generation | 2nd |
| Phase | Phase1 |
| Recruitment status | Terminated |
| Title | Safety and Toxicity of CAR-T Cell Immunotherapy in Patients With Advanced Lung Cancer After Standard Treatment Failure: A Single-Arm and Single-Center Phase I Clinical Study |
| Year | 2017 |
| Country | China |
| Company sponsor | Sun Yat-sen University |
| Other ID(s) | CART-YY2017 |
| Vector information | |||||
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| Cohort 1 | |||||||||||||
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