Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC1813
Trial ID NCT03330691
Disease Leukemia | Lymphoma
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleA Feasibility and Safety Study of Dual Specificity CD19 and CD22 CAR-T Cell Immunotherapy for CD19+CD22+ Leukemia
Year2017
CountryUnited States
Company sponsorSeattle Children's Hospital
Other ID(s)PLAT-05

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 80
Age Child, Adult
References PMID: 34244298

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