Basic Information

Gene symbol KRT31 Synonyms HA1, Ha-1, KRTHA1, hHa1 Type of gene protein-coding
Description keratin 31

GTO ID GTC1810
Trial ID NCT03326921
Disease Leukemia | Myelodysplastic Syndrome
Altered gene HA1
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment HA-1 TCR-T cells
HLAHLA-A*02:01
PhasePhase1
Recruitment statusSuspended
TitlePhase I Study of Adoptive Immunotherapy With CD8+ and CD4+ Memory T Cells Transduced to Express an HA-1-Specific T Cell Receptor (TCR) for Children and Adults With Recurrent Acute Leukemia After Allogeneic Hematopoietic Stem Cell Transplantation (HCT)
Year2017
CountryUnited States
Company sponsorFred Hutchinson Cancer Center
Other ID(s)9716|NCI-2017-01054|9716|RG9217022

Clinical Result

Cohort 1
Administration route infusion
Age Child, Adult, Older_Adult
Lymph depletion Yes

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