Basic Information

Gene symbol tk

GTO ID GTC1800
Trial ID NCT03313596
Disease Hepatocellular Carcinoma
Altered gene tk
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment Adv-HSV-tk
PhasePhase3
Recruitment statusUnknown
TitleTreatment of Severe Combined Immunodeficiency Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency With Autologous Lymphocytes of CD34+ Cells Transduced With a Human ADA Gene: A Natural History Study
Year2017
CountryChina
Company sponsorHuazhong University of Science and Technology
Other ID(s)LT-03
Vector information
Vectoradenovirus
ConstructAdV-tk
Vector typeadenoviral vector
Transgene/Inserted geneherpes simplex virus (HSV) thymidine kinase gene

Clinical Result

Cohort 1
Administration route injection
Dosage 1.0E12 viral particles on day 0, 60, 90
Age Adult, Older_Adult

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