Gene symbol | KLRK1 | Synonyms | CD314, D12S2489E, KLR, NKG2-D, NKG2D | Type of gene | protein-coding |
Chromosome | 12 | Map location | 12p13.2 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | killer cell lectin like receptor K1 |
GTO ID | GTC1797 |
Trial ID | NCT03310008 |
Disease | Colon Cancer |
Altered gene | NKG2D |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | NKG2D CAR-T cells |
Co-treatment | FOLFOX |
Phase | Phase1 |
Recruitment status | Unknown |
Title | Dose Escalation and Dose Expansion Phase I Study to Assess the Safety and Clinical Activity of Multiple Doses of NKR-2 Administered Concurrently With FOLFOX in Colorectal Cancer With Potentially Resectable Liver Metastases |
Year | 2017 |
Country | Belgium |
Company sponsor | Celyad Oncology SA |
Other ID(s) | CYAD-N2T-003 |
Cohort 1 | |||||||||
|