Basic Information

Gene symbol KLRK1 Synonyms CD314, D12S2489E, KLR, NKG2-D, NKG2D Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description killer cell lectin like receptor K1

GTO ID GTC1797
Trial ID NCT03310008
Disease Colon Cancer
Altered gene NKG2D
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment NKG2D CAR-T cells
Co-treatment FOLFOX
PhasePhase1
Recruitment statusUnknown
TitleDose Escalation and Dose Expansion Phase I Study to Assess the Safety and Clinical Activity of Multiple Doses of NKR-2 Administered Concurrently With FOLFOX in Colorectal Cancer With Potentially Resectable Liver Metastases
Year2017
CountryBelgium
Company sponsorCelyad Oncology SA
Other ID(s)CYAD-N2T-003

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 36
Age Adult, Older_Adult

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