Gene symbol | TNFRSF17 | Synonyms | BCM, BCMA, CD269, TNFRSF13A | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p13.13 | dbXrefs | |
Description | TNF receptor superfamily member 17 |
Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | CLDN18 | Synonyms | SFTA5, SFTPJ | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3q22.3 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | claudin 18 |
Gene symbol | GPC3 | Synonyms | DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 | Type of gene | protein-coding |
Chromosome | X | Map location | Xq26.2 | dbXrefs | |
Description | glypican 3 |
GTO ID | GTC1795 |
Trial ID | NCT03302403 |
Disease | B-Cell Leukemia | B-Cell Lymphoma | Pancreatic Carcinoma | Hepatocellular Carcinoma | Multiple Myeloma | Adenocarcinoma of Esophagogastric Junction |
Altered gene | CD19|BCMA|GPC3|CLDN18 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | BCMA/CD19/CLDN18/GPC3 CAR-T cells |
Recruitment status | Active, Not Recruiting |
Title | Clinical Study of Redirected Autologous T Cells With a Chimeric Antigen Receptor in Patients With Malignant Tumors |
Year | 2017 |
Country | China |
Company sponsor | First Affiliated Hospital of Wenzhou Medical University |
Other ID(s) | CGZ001 |
Vector information | |||
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Cohort 1 | |||||||||||
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