Gene symbol | AR | Synonyms | AIS, AR8, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM | Type of gene | protein-coding |
Chromosome | X | Map location | Xq12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | androgen receptor |
GTO ID | GTC1794 |
Trial ID | NCT03300505 |
Disease | Prostate Cancer |
Altered gene | AR |
Therapeutic/Target gene | Target gene |
Therapy | ASO |
Treatment | AZD5312|ISIS 560131|ARRx |
Co-treatment | Enzalutamide |
Phase | Phase1 |
Recruitment status | Terminated |
Title | ARRO-CITO: (UMCC 2017.055) Phase Ib/II Single-Arm Multi-Center Study of IONIS-AR-2.5Rx, a Next Generation Androgen Receptor Antisense Oligonucleotide, in Combination With Enzalutamide in Metastatic Castration Resistant Prostate Cancer |
Year | 2019 |
Country | United States |
Company sponsor | University of Michigan Rogel Cancer Center |
Other ID(s) | UMCC 2017.055|HUM00130051 |
Vector information | |||
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Cohort 1 | |||||||||
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