Basic Information


GTO ID GTC1791
Trial ID NCT03294954
Disease Neuroblastoma
Altered gene GD2
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment GD2 CAR-T cells
Generation2nd
PhasePhase1
Recruitment statusActive, Not Recruiting
TitleGD2 Specific CAR and Interleukin-15 Expressing Autologous NKT Cells to Treat Children With Neuroblastoma
Year2018
CountryUnited States
Company sponsorBaylor College of Medicine
Other ID(s)H-41033 GINAKIT2

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 3E6 cells/kg, 1E7 cells/kg, 3E7 cells/kg, 1E8 cells/kg, 3E8 cells/kg, 1E9 cells/kg
Donor type Autologous
Pts 36
Age Child, Adult
Lymph depletion Yes
References PMID: 33046868 | 31484667

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