Basic Information

Gene symbol MME Synonyms CALLA, CD10, CMT2T, NEP, SCA43, SFE Type of gene protein-coding
Description membrane metalloendopeptidase

Gene symbol KIT Synonyms C-Kit, CD117, MASTC, PBT, SCFR Type of gene protein-coding
Gene perturbation-related omics dataset PertOrg
Description KIT proto-oncogene, receptor tyrosine kinase

Gene symbol IL3RA Synonyms CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra Type of gene protein-coding
Description interleukin 3 receptor subunit alpha

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

Gene symbol CD33 Synonyms CD33rSiglec, SIGLEC-3, SIGLEC3, p67 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD33 molecule

Gene symbol CD34 Synonyms None Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD34 molecule

Gene symbol CD38 Synonyms ADPRC 1, ADPRC1, cADPR1 Type of gene protein-coding
Gene perturbation-related omics dataset PertOrg
Description CD38 molecule

Gene symbol NCAM1 Synonyms CD56, MSK39, NCAM Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description neural cell adhesion molecule 1

Gene symbol MUC1 Synonyms ADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description mucin 1, cell surface associated

GTO ID GTC1789
Trial ID NCT03291444
Disease Acute Lymphoblastic Leukemia | Acute Myeloid Leukemia | Myelodysplastic Syndrome
Altered gene CD19|CD20|CD22|CD10|CD33|CD38|CD56|CD117|CD123|CD34|MUC1
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CAR-T cells
Co-treatment Eps8 peptide specific dendritic cell
PhasePhase1
Recruitment statusRecruiting
TitleCAR-T Cells Combined With Peptide Specific Dendritic Cell in Relapsed/Refractory Leukemia/MDS
Year2017
CountryChina
Company sponsorZhujiang Hospital
Other ID(s)2017-XYNK-001

Clinical Result

Cohort1: CAR-T cells combined with peptide specific dendritic cell
Administration route None
Age Adult, Older_Adult
Cohort2: CAR-T cells
Administration route None
Age Adult, Older_Adult

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