Gene symbol | MME | Synonyms | CALLA, CD10, CMT2T, NEP, SCA43, SFE | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3q25.2 | dbXrefs | |
Description | membrane metalloendopeptidase |
Gene symbol | KIT | Synonyms | C-Kit, CD117, MASTC, PBT, SCFR | Type of gene | protein-coding |
Chromosome | 4 | Map location | 4q12 | dbXrefs | |
Gene perturbation-related omics dataset | PertOrg | ||||
Description | KIT proto-oncogene, receptor tyrosine kinase |
Gene symbol | IL3RA | Synonyms | CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra | Type of gene | protein-coding |
Chromosome | X|Y | Map location | X;Y | dbXrefs | |
Description | interleukin 3 receptor subunit alpha |
Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | MS4A1 | Synonyms | B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q12.2 | dbXrefs | |
Description | membrane spanning 4-domains A1 |
Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD22 molecule |
Gene symbol | CD33 | Synonyms | CD33rSiglec, SIGLEC-3, SIGLEC3, p67 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.41 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | CD33 molecule |
Gene symbol | CD34 | Synonyms | None | Type of gene | protein-coding |
Chromosome | 1 | Map location | 1q32.2 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | CD34 molecule |
Gene symbol | CD38 | Synonyms | ADPRC 1, ADPRC1, cADPR1 | Type of gene | protein-coding |
Chromosome | 4 | Map location | 4p15.32 | dbXrefs | |
Gene perturbation-related omics dataset | PertOrg | ||||
Description | CD38 molecule |
Gene symbol | NCAM1 | Synonyms | CD56, MSK39, NCAM | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q23.2 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | neural cell adhesion molecule 1 |
Gene symbol | MUC1 | Synonyms | ADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM | Type of gene | protein-coding |
Chromosome | 1 | Map location | 1q22 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | mucin 1, cell surface associated |
GTO ID | GTC1789 |
Trial ID | NCT03291444 |
Disease | Acute Lymphoblastic Leukemia | Acute Myeloid Leukemia | Myelodysplastic Syndrome |
Altered gene | CD19|CD20|CD22|CD10|CD33|CD38|CD56|CD117|CD123|CD34|MUC1 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CAR-T cells |
Co-treatment | Eps8 peptide specific dendritic cell |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | CAR-T Cells Combined With Peptide Specific Dendritic Cell in Relapsed/Refractory Leukemia/MDS |
Year | 2017 |
Country | China |
Company sponsor | Zhujiang Hospital |
Other ID(s) | 2017-XYNK-001 |
Cohort1: CAR-T cells combined with peptide specific dendritic cell | |||||
|
|||||
Cohort2: CAR-T cells | |||||
|