Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC1788
Trial ID NCT03289455
Disease B-Cell Acute Lymphoblastic Leukemia | Acute Lymphoblastic Leukemia | Childhood B-Cell Acute Lymphoblastic Leukemia | Childhood Acute Lymphoblastic Leukemia
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment AUTO3
PhasePhase1|Phase2
Recruitment statusCompleted
TitleCD19 /22 CAR T Cells (AUTO3) for the Treatment of B Cell Acute Lymphoblastic Leukemia (ALL)
Year2017
CountryUnited Kingdom
Company sponsorAutolus Limited
Other ID(s)AUTO3-PA1|2016-004680-39

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 23
Age Child, Adult

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