Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD22 molecule |
GTO ID | GTC1788 |
Trial ID | NCT03289455 |
Disease | B-Cell Acute Lymphoblastic Leukemia | Acute Lymphoblastic Leukemia | Childhood B-Cell Acute Lymphoblastic Leukemia | Childhood Acute Lymphoblastic Leukemia |
Altered gene | CD19|CD22 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | AUTO3 |
Phase | Phase1|Phase2 |
Recruitment status | Completed |
Title | CD19 /22 CAR T Cells (AUTO3) for the Treatment of B Cell Acute Lymphoblastic Leukemia (ALL) |
Year | 2017 |
Country | United Kingdom |
Company sponsor | Autolus Limited |
Other ID(s) | AUTO3-PA1|2016-004680-39 |
Cohort 1 | |||||||
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