Basic Information

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

GTO ID GTC1780
Trial ID NCT03277729
Disease B-Cell Non-Hodgkin's Lymphoma
Altered gene CD20
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD20 CAR-T cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleA Phase I/II Study to Evaluate the Safety of Cellular Immunotherapy Using Autologous T Cells Engineered to Express a CD20-Specific Chimeric Antigen Receptor for Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphomas
Year2017
CountryUnited States
Company sponsorFred Hutchinson Cancer Center
Other ID(s)9738|NCI-2017-01595|9738|RG9217017

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 50
Age Adult, Older_Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph