Basic Information

Gene symbol MAGEA4 Synonyms CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B Type of gene protein-coding
Description MAGE family member A4

Gene symbol MAGEA8 Synonyms CT1.8, MAGE8 Type of gene protein-coding
Description MAGE family member A8

GTO ID GTC1766
Trial ID NCT03247309
Disease Solid Tumor
Altered gene MAGE-A4|MAGE-A8
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment IMA201
PhasePhase1
Recruitment statusActive, Not Recruiting
TitlePhase 1 Study Evaluating Genetically Modified Autologous T Cells Expressing a T-cell Receptor Recognizing a Cancer/Germline Antigen in Patients With Recurrent and/or Refractory Solid Tumors (ACTengine IMA201-101)
Year2017
CountryUnited States|Germany
Company sponsorImmatics US, Inc.
Other ID(s)IMA201-101

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Age Adult, Older_Adult
Lymph depletion Yes

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