Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC1761
Trial ID NCT03233854
Disease Acute Lymphoblastic Leukemia
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
Generation2nd
PhasePhase1
Recruitment statusRecruiting
TitleCD19/CD22 Chimeric Antigen Receptor (CAR) T Cells With or Without NKTR-255 in Adults With Recurrent or Refractory B Cell Malignancies
Year2017
CountryUnited States
Company sponsorStanford University
Other ID(s)IRB-41382|41382|CCT5001

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E6 cells/kg, 3E6 cells/kg
Pts 60
Age Adult, Older_Adult
Lymph depletion Yes

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