Gene symbol | IL3RA | Synonyms | CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra | Type of gene | protein-coding | |
Chromosome | X|Y | Map location | X;Y | dbXrefs | Entrez:3563 MIM:308385 MIM:430000 HGNC:HGNC:6012 Ensembl:ENSG00000185291 Ensembl:ENSG00000292332 AllianceGenome:HGNC:6012 | |
Description | interleukin 3 receptor subunit alpha |
Gene symbol | CD33 | Synonyms | CD33rSiglec, SIGLEC-3, SIGLEC3, p67 | Type of gene | protein-coding | |
Chromosome | 19 | Map location | 19q13.41 | dbXrefs | Entrez:945 MIM:159590 HGNC:HGNC:1659 Ensembl:ENSG00000105383 AllianceGenome:HGNC:1659 | |
Gene perturbation-related omics dataset | PerturbAtlas | |||||
Description | CD33 molecule |
Gene symbol | CD38 | Synonyms | ADPRC 1, ADPRC1, cADPR1 | Type of gene | protein-coding | |
Chromosome | 4 | Map location | 4p15.32 | dbXrefs | Entrez:952 MIM:107270 HGNC:HGNC:1667 Ensembl:ENSG00000004468 AllianceGenome:HGNC:1667 | |
Gene perturbation-related omics dataset | PertOrg | |||||
Description | CD38 molecule |
Gene symbol | NCAM1 | Synonyms | CD56, MSK39, NCAM | Type of gene | protein-coding | |
Chromosome | 11 | Map location | 11q23.2 | dbXrefs | Entrez:4684 MIM:116930 HGNC:HGNC:7656 Ensembl:ENSG00000149294 AllianceGenome:HGNC:7656 | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | |||||
Description | neural cell adhesion molecule 1 |
Gene symbol | COLEC10 | Synonyms | 3MC3, CL-10, CL-34, CLL1 | Type of gene | protein-coding | |
Chromosome | 8 | Map location | 8q24.12 | dbXrefs | Entrez:10584 MIM:607620 HGNC:HGNC:2220 Ensembl:ENSG00000184374 AllianceGenome:HGNC:2220 | |
Description | collectin subfamily member 10 |
Gene symbol | MUC1 | Synonyms | ADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM | Type of gene | protein-coding | |
Chromosome | 1 | Map location | 1q22 | dbXrefs | Entrez:4582 MIM:158340 HGNC:HGNC:7508 Ensembl:ENSG00000185499 AllianceGenome:HGNC:7508 | |
Gene perturbation-related omics dataset | PerturbAtlas | |||||
Description | mucin 1, cell surface associated |
GTO ID | GTC1758 |
Trial ID | NCT03222674 |
Disease | Acute Myeloid Leukemia |
Altered gene | MUC1|CLL1|CD33|CD38|CD56|CD123 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CAR-T cells |
Phase | Phase1|Phase2 |
Recruitment status | Unknown |
Title | Multi-CAR T Cell Therapy for Acute Myeloid Leukemia |
Year | 2017 |
Country | China |
Company sponsor | Shenzhen Geno-Immune Medical Institute |
Other ID(s) | GIMI-IRB-17015 |
Cohort 1 | |||||||
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