Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC1755
Trial ID NCT03208556
Disease B-Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
Generation2nd
PhasePhase1
Recruitment statusUnknown
TitleSafety and Efficacy of iPD1 CD19 eCAR T Cells in Relapsed or Refractory B-cell Lymphoma
Year2017
CountryChina
Company sponsorPeking University
Other ID(s)2017YJZ13
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route None
Dosage 1E5 cells/kg, 1E6 cells/kg, 3E6 cells/kg, 6E6 cells/kg
Pts 20
Age Adult, Older_Adult
Lymph depletion Yes

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