Basic Information

Gene symbol GPC3 Synonyms DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 Type of gene protein-coding
Description glypican 3

Gene symbol TGFB1 Synonyms CED, DPD1, IBDIMDE, LAP, TGF-beta1, TGFB, TGFbeta Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description transforming growth factor beta 1

GTO ID GTC1751
Trial ID NCT03198546
Disease Hepatocellular Carcinoma | Lung Squamous Cell Carcinoma
Altered gene GPC3|TGFB1
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment GPC3/TGFβ CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleGPC3-CAR-T Cells for Immunotherapy of Cancer With GPC3 Expression
Year2017
CountryChina
Company sponsorSecond Affiliated Hospital of Guangzhou Medical University
Other ID(s)ZZCART-003

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 30
Age Adult, Older_Adult
References PMID: 28123387 | 34325726

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