Gene symbol | GPC3 | Synonyms | DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 | Type of gene | protein-coding |
Chromosome | X | Map location | Xq26.2 | dbXrefs | |
Description | glypican 3 |
Gene symbol | TGFB1 | Synonyms | CED, DPD1, IBDIMDE, LAP, TGF-beta1, TGFB, TGFbeta | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.2 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | transforming growth factor beta 1 |
GTO ID | GTC1751 |
Trial ID | NCT03198546 |
Disease | Hepatocellular Carcinoma | Lung Squamous Cell Carcinoma |
Altered gene | GPC3|TGFB1 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | GPC3/TGFβ CAR-T cells |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | GPC3-CAR-T Cells for Immunotherapy of Cancer With GPC3 Expression |
Year | 2017 |
Country | China |
Company sponsor | Second Affiliated Hospital of Guangzhou Medical University |
Other ID(s) | ZZCART-003 |
Cohort 1 | |||||||||||
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