| Gene symbol | AXL | Synonyms | ARK, AXL3, JTK11, Tyro7, UFO | Type of gene | protein-coding |
| Chromosome | 19 | Map location | 19q13.2 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | AXL receptor tyrosine kinase | ||||
| Gene symbol | CD276 | Synonyms | 4Ig-B7-H3, B7-H3, B7H3, B7RP-2 | Type of gene | protein-coding |
| Chromosome | 15 | Map location | 15q24.1 | dbXrefs | |
| Description | CD276 molecule | ||||
| Gene symbol | CLDN18 | Synonyms | SFTA5, SFTPJ | Type of gene | protein-coding |
| Chromosome | 3 | Map location | 3q22.3 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | claudin 18 | ||||
| Gene symbol | EGFR | Synonyms | ERBB, ERBB1, ERRP, HER1, NISBD2, PIG61, mENA | Type of gene | protein-coding |
| Chromosome | 7 | Map location | 7p11.2 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | epidermal growth factor receptor | ||||
| Gene symbol | GPC3 | Synonyms | DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 | Type of gene | protein-coding |
| Chromosome | X | Map location | Xq26.2 | dbXrefs | |
| Description | glypican 3 | ||||
| Gene symbol | GUCY2C | Synonyms | DIAR6, GC-C, GCC, GUC2C, HSER, MECIL, MUCIL, STAR | Type of gene | protein-coding |
| Chromosome | 12 | Map location | 12p12.3 | dbXrefs | |
| Description | guanylate cyclase 2C | ||||
| Gene symbol | ERBB2 | Synonyms | CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2) | Type of gene | protein-coding |
| Chromosome | 17 | Map location | 17q12 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | erb-b2 receptor tyrosine kinase 2 | ||||
| Gene symbol | MUC1 | Synonyms | ADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM | Type of gene | protein-coding |
| Chromosome | 1 | Map location | 1q22 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | ||||
| Description | mucin 1, cell surface associated | ||||
| Gene symbol | PSCA | Synonyms | PRO232, lncPSCA | Type of gene | protein-coding |
| Chromosome | 8 | Map location | 8q24.3 | dbXrefs | |
| Description | prostate stem cell antigen | ||||
| Gene symbol | FOLH1 | Synonyms | FGCP, FOLH, GCP2, GCPII, NAALAD1, PSM, PSMA, mGCP | Type of gene | protein-coding |
| Chromosome | 11 | Map location | 11p11.12 | dbXrefs | |
| Description | folate hydrolase 1 | ||||
| Gene symbol | TGFB1 | Synonyms | CED, DPD1, IBDIMDE, LAP, TGF-beta1, TGFB, TGFbeta | Type of gene | protein-coding |
| Chromosome | 19 | Map location | 19q13.2 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | transforming growth factor beta 1 | ||||
| GTO ID | GTC1750 |
| Trial ID | NCT03198052 |
| Disease | Lung Cancer |
| Altered gene | GPC3|MESO|CLDN18|GUCY2C|CD276|PSCA|PSMA|MUC1|TGFB1|HER2|LeY|AXL|EGFR |
| Therapeutic/Target gene | Target gene |
| Therapy | CAR-T cell |
| Treatment | CAR-T cells |
| Generation | 3rd |
| Phase | Phase1 |
| Recruitment status | Recruiting |
| Title | CAR-T Targeting GPC3, Mesothelin, Claudin18.2, GUCY2C, B7-H3, PSCA, PSMA, MUC1, TGFβ, HER2, Lewis-Y, AXL, or EGFR for Immunotherapy of Lung Cancer: Phase I Clinical Trial |
| Year | 2017 |
| Country | China |
| Company sponsor | Second Affiliated Hospital of Guangzhou Medical University |
| Other ID(s) | ZZCART-002 |
| Cohort 1 | |||||||||
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