Gene symbol | TERT | Synonyms | CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT | Type of gene | protein-coding |
Chromosome | 5 | Map location | 5p15.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | telomerase reverse transcriptase |
GTO ID | GTC1746 |
Trial ID | NCT03190824 |
Disease | Melanoma |
Altered gene | E1A|E1B|TERT |
Therapeutic/Target gene | Therapeutic gene |
Therapy | DNA oncolytic virus |
Treatment | Telomelysin|OBP-301 |
Phase | Phase2 |
Recruitment status | Unknown |
Title | Open-label, Multi-center Phase IIa Study to Evaluate the Efficacy, Safety, and Immunological Response of OBP-301, Telomerase Specific Replication-competent Oncolytic Adenovirus in Patients With Unresectable Metastatic Melanoma |
Year | 2017 |
Country | United States |
Company sponsor | Syneos Health |
Other ID(s) | TL03001|Interventional |
Vector information | |||||||||||
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