Basic Information

Gene symbol MUC1 Synonyms ADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description mucin 1, cell surface associated

GTO ID GTC1739
Trial ID NCT03179007
Disease Advanced Solid Tumor
Altered gene MUC1
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment MUC-1 CAR-T cells
PhasePhase1|Phase2
Recruitment statusUnknown
TitleCTLA-4 and PD-1 Antibodies Expressing MUC1-CAR-T Cells for MUC1 Positive Advanced Solid Tumor
Year2017
CountryChina
Company sponsorShanghai Cell Therapy Research Institute
Other ID(s)H2017-04-P01

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 2~5E7 cells/kg
Donor type Autologous
Pts 40
Age Adult, Older_Adult
Lymph depletion Yes

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