Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC1735
Trial ID NCT03166878
Disease B-Cell Lymphoma | B-Cell Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment UCAR-T019
Generation2nd
PhasePhase1|Phase2
Recruitment statusUnknown
TitleA Study Evaluating UCART019 in Patients With Relapsed or Refractory CD19+ Leukemia and Lymphoma
Year2017
CountryChina
Company sponsorChinese PLA General Hospital
Other ID(s)CHN-PLAGH-BT-021
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route None
Dosage 10% on day 0, 30% on day 1 and 60% on day 2
Donor type Allogeneic
Pts 80
Age Child, Adult, Older_Adult

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