Basic Information

Gene symbol CLDN18 Synonyms SFTA5, SFTPJ Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description claudin 18

GTO ID GTC1733
Trial ID NCT03159819
Disease Pancreatic Adenocarcinoma | Gastric Adenocarcinoma
Altered gene CLDN18
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CLDN18.2 CAR-T cells
Recruitment statusUnknown
TitleClinical Study of CAR-CLD18 T Cells in Patients With Advanced Gastric Adenocarcinoma and Pancreatic Adenocarcinoma
Year2017
CountryChina
Company sponsorChanghai Hospital
Other ID(s)CG4003
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 24
Age Adult, Older_Adult
Lymph depletion Yes

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