Basic Information

Gene symbol MAGEA3 Synonyms CT1.3, HIP8, HYPD, MAGE3, MAGEA6 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description MAGE family member A3

Gene symbol MAGEA6 Synonyms CT1.6, MAGE-3b, MAGE3B, MAGE6 Type of gene protein-coding
Description MAGE family member A6

GTO ID GTC1724
Trial ID NCT03139370
Disease Solid Tumor
Altered gene MAGE-A3|MAGE-A6
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment KITE-718
HLAHLA-DPB1*04:01
PhasePhase1
Recruitment statusTerminated
TitleA Phase 1 Study Evaluating the Safety and Efficacy of MAGE-A3/A6 T Cell Receptor Engineered T Cells (KITE-718) in HLA-DPB1*04:01 Positive Subjects With Advanced Cancers
Year2017
CountryUnited States
Company sponsorKite, A Gilead Company
Other ID(s)KITE-718-301|2020-005456-37

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Age Adult, Older_Adult
Lymph depletion Yes

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