Gene symbol | MAGEA3 | Synonyms | CT1.3, HIP8, HYPD, MAGE3, MAGEA6 | Type of gene | protein-coding | |
Chromosome | X | Map location | Xq28 | dbXrefs | Entrez:4102 MIM:300174 HGNC:HGNC:6801 Ensembl:ENSG00000221867 AllianceGenome:HGNC:6801 | |
Gene perturbation-related omics dataset | PerturbAtlas | |||||
Description | MAGE family member A3 |
Gene symbol | MAGEA6 | Synonyms | CT1.6, MAGE-3b, MAGE3B, MAGE6 | Type of gene | protein-coding | |
Chromosome | X | Map location | Xq28 | dbXrefs | Entrez:4105 MIM:300176 HGNC:HGNC:6804 Ensembl:ENSG00000197172 AllianceGenome:HGNC:6804 | |
Description | MAGE family member A6 |
GTO ID | GTC1724 |
Trial ID | NCT03139370 |
Disease | Solid Tumor |
Altered gene | MAGE-A3|MAGE-A6 |
Therapeutic/Target gene | Target gene |
Therapy | TCR-T cell |
Treatment | KITE-718 |
HLA | HLA-DPB1*04:01 |
Phase | Phase1 |
Recruitment status | Terminated |
Title | A Phase 1 Study Evaluating the Safety and Efficacy of MAGE-A3/A6 T Cell Receptor Engineered T Cells (KITE-718) in HLA-DPB1*04:01 Positive Subjects With Advanced Cancers |
Year | 2017 |
Country | United States |
Company sponsor | Kite, A Gilead Company |
Other ID(s) | KITE-718-301|2020-005456-37 |
Cohort 1 | |||||||||
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