| Gene symbol | AFP | Synonyms | AFPD, FETA, HPAFP | Type of gene | protein-coding |
| Chromosome | 4 | Map location | 4q13.3 | dbXrefs | |
| Gene perturbation-related omics dataset | PertOrg | ||||
| Description | alpha fetoprotein | ||||
| GTO ID | GTC1722 |
| Trial ID | NCT03132792 |
| Disease | Hepatocellular Carcinoma |
| Altered gene | AFP |
| Therapeutic/Target gene | Target gene |
| Therapy | TCR-T cell |
| Treatment | AFP TCR-T cells |
| HLA | HLA-A*02:01|HLA-A*02:03 |
| Phase | Phase1 |
| Recruitment status | Active, Not Recruiting |
| Title | A Phase I Open Label Clinical Trial Evaluating the Safety and Anti-Tumor Activity of Autologous T Cells Expressing Enhanced TCRs Specific for Alpha Fetoprotein (AFPC332T) in HLA-A2 Positive Subjects With Advanced Hepatocellular Carcinoma (HCC) or Other AFP Expressing Tumor Types |
| Year | 2017 |
| Country | United States |
| Company sponsor | Adaptimmune |
| Other ID(s) | ADP-0033-001 |
| Cohort 1 | |||||||||
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