Gene symbol | IL3RA | Synonyms | CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra | Type of gene | protein-coding |
Chromosome | X|Y | Map location | X;Y | dbXrefs | |
Description | interleukin 3 receptor subunit alpha |
Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | MS4A1 | Synonyms | B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q12.2 | dbXrefs | |
Description | membrane spanning 4-domains A1 |
Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD22 molecule |
Gene symbol | TNFRSF8 | Synonyms | CD30, D1S166E, Ki-1 | Type of gene | protein-coding |
Chromosome | 1 | Map location | 1p36.22 | dbXrefs | |
Description | TNF receptor superfamily member 8 |
Gene symbol | CD38 | Synonyms | ADPRC 1, ADPRC1, cADPR1 | Type of gene | protein-coding |
Chromosome | 4 | Map location | 4p15.32 | dbXrefs | |
Gene perturbation-related omics dataset | PertOrg | ||||
Description | CD38 molecule |
Gene symbol | CD70 | Synonyms | CD27-L, CD27L, CD27LG, LPFS3, TNFSF7, TNLG8A | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19p13.3 | dbXrefs | |
Description | CD70 molecule |
GTO ID | GTC1720 |
Trial ID | NCT03125577 |
Disease | B-Cell Malignancy |
Altered gene | CD19|CD20|CD22|CD30|CD38|CD70|CD123 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CAR-T cells |
Generation | 4th |
Phase | Phase1|Phase2 |
Recruitment status | Unknown |
Title | Combination CAR-T Cell Therapy Targeting Hematological Malignancies |
Year | 2017 |
Country | China |
Company sponsor | Shenzhen Geno-Immune Medical Institute |
Other ID(s) | GIMI-IRB-17005 |
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