Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC1713
Trial ID NCT03105336
Disease Non-Hodgkin's Lymphoma | Marginal Zone Lymphoma | Follicular Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment YesCAR-Ta|Axicabtagene Ciloleucel|axi-cel
Generation2nd
PhasePhase2
Recruitment statusActive, Not Recruiting
TitleA Phase 2 Multicenter Study of Axicabtagene Ciloleucel in Subjects With Relapsed/Refractory Indolent Non-Hodgkin Lymphoma
Year2017
CountryFrance|United States
Company sponsorKite, A Gilead Company
Other ID(s)KTE-C19-105|2017-001912-13
Vector information
Vectorlentivirus
ConstructscFv-CD28-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 159
Age Adult, Older_Adult
Lymph depletion Yes

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