Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD22 molecule |
GTO ID | GTC1710 |
Trial ID | NCT03098355 |
Disease | B-Cell Leukemia | B-Cell Lymphoma |
Altered gene | CD19|CD22 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD19/CD22 CAR-T cells |
Generation | 4th |
Phase | Phase1|Phase2 |
Recruitment status | Suspended |
Title | Interleukin-2 Following 4SCAR19/22 T Cells Targeting Refractory and/or Recurrent B Cell Malignancies |
Year | 2017 |
Country | China |
Company sponsor | Zhujiang Hospital |
Other ID(s) | anti-CD19/22 cells |
Vector information | |||||||
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Cohort 1 | |||||||||||||
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