Gene symbol | PCSK9 | Synonyms | FH3, FHCL3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9 | Type of gene | protein-coding |
Chromosome | 1 | Map location | 1p32.3 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | proprotein convertase subtilisin/kexin type 9 |
GTO ID | GTC1708 |
Trial ID | NCT03087591 |
Disease | Colorectal Cancer | Colorectal Carcinoma | Pancreatic Carcinoma | Solid Neoplasm | Pancreatic Cancer | Metastatic Malignant Neoplasm |
Altered gene | PCSK9 |
Therapeutic/Target gene | Target gene |
Therapy | siRNA |
Treatment | APN401 |
Phase | Phase1 |
Recruitment status | Completed |
Title | Safety and Immunologic Activity of Multiple Infusions of APN401 |
Year | 2017 |
Country | United States |
Company sponsor | Wake Forest University Health Sciences |
Other ID(s) | IRB00041173|NCI-2017-00050|CCCWFU 03716|P30CA012197 |
Vector information | |||
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Cohort 1 | |||||||||
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