Basic Information

Gene symbol PCSK9 Synonyms FH3, FHCL3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description proprotein convertase subtilisin/kexin type 9

GTO ID GTC1708
Trial ID NCT03087591
Disease Colorectal Cancer | Colorectal Carcinoma | Pancreatic Carcinoma | Solid Neoplasm | Pancreatic Cancer | Metastatic Malignant Neoplasm
Altered gene PCSK9
Therapeutic/Target gene Target gene
TherapysiRNA
Treatment APN401
PhasePhase1
Recruitment statusCompleted
TitleSafety and Immunologic Activity of Multiple Infusions of APN401
Year2017
CountryUnited States
Company sponsorWake Forest University Health Sciences
Other ID(s)IRB00041173|NCI-2017-00050|CCCWFU 03716|P30CA012197
Vector information
VectorGalNAc

Clinical Result

Cohort 1
Administration route intravenous injection
Pts 11
Age Adult, Older_Adult
References PMID: 35362047

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