Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC1706
Trial ID NCT03085173
Therapeutic/Target gene 39
Therapycancer
Treatment Chronic Lymphocytic Leukemia
Co-treatment ex vivo
GenerationAdult, Older_Adult
PhasePhase1
Recruitment statusActive, Not Recruiting
TitleA Trial of Armored" CAR T Cells Targeting CD19 For Patients With Relapsed CD19+ Hematologic Malignancies Genetically-modified cell therapy CAR-T cell CD19 CAR-T cells CD19 Target gene 4th retrovirus scFv-CD28-4-1BB-CD3ζ 19-28z CAR; 4-1BBL EGFRt "1E5 cells/kg, 3E5 cells/kg, 1E6 cells/kg, 3E6 cells/kg
Year2017
CountryUnited States
Vector information
VectorYes
Vector production methodother
Additional featureMemorial Sloan Kettering Cancer Center

Clinical Result

https://pubmed.ncbi.nlm.nih.gov/35173030/
Administration route 16-1570
Dosage PMID: 35173030

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