Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
GTO ID | GTC1706 |
Trial ID | NCT03085173 |
Therapeutic/Target gene | 39 |
Therapy | cancer |
Treatment | Chronic Lymphocytic Leukemia |
Co-treatment | ex vivo |
Generation | Adult, Older_Adult |
Phase | Phase1 |
Recruitment status | Active, Not Recruiting |
Title | A Trial of Armored" CAR T Cells Targeting CD19 For Patients With Relapsed CD19+ Hematologic Malignancies Genetically-modified cell therapy CAR-T cell CD19 CAR-T cells CD19 Target gene 4th retrovirus scFv-CD28-4-1BB-CD3ζ 19-28z CAR; 4-1BBL EGFRt "1E5 cells/kg, 3E5 cells/kg, 1E6 cells/kg, 3E6 cells/kg |
Year | 2017 |
Country | United States |
Vector information | |||||||
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https://pubmed.ncbi.nlm.nih.gov/35173030/ | |||||
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