Gene symbol | PMEL | Synonyms | D12S53E, HMB-45, HMB45, ME20, ME20-M, ME20M, P1, P100, PMEL17, SI, SIL, SILV, gp100 | Type of gene | protein-coding |
Chromosome | 12 | Map location | 12q13.2 | dbXrefs | |
Description | premelanosome protein |
GTO ID | GTC1701 |
Trial ID | NCT03070392 |
Disease | Uveal Melanoma |
Altered gene | gp100 |
Therapeutic/Target gene | Target gene |
Therapy | TCR-T cell |
Treatment | gp100 TCR-T cells |
HLA | HLA-A*02:01 |
Phase | Phase2 |
Recruitment status | Active, Not Recruiting |
Title | A Phase II Randomized, Open-label, Multi-center Study of the Safety and Efficacy of IMCgp100 Compared With Investigator Choice in HLA-A*0201 Positive Patients With Previously Untreated Advanced Uveal Melanoma |
Year | 2017 |
Country | United States |
Company sponsor | Immunocore Ltd |
Other ID(s) | IMCgp100-202 |
Cohort 1 | |||||||||||
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