Gene symbol | MET | Synonyms | AUTS9, DA11, DFNB97, HGFR, RCCP2, c-Met | Type of gene | protein-coding |
Chromosome | 7 | Map location | 7q31.2 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | MET proto-oncogene, receptor tyrosine kinase |
GTO ID | GTC1697 |
Trial ID | NCT03060356 |
Disease | Malignant Adenoma | Breast Cancer |
Altered gene | c-MET |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | cMet CAR-T cells |
Generation | 2nd |
Phase | Early_Phase1 |
Recruitment status | Terminated |
Title | Autologous T Cells Expressing MET scFv CAR (RNA CART-cMET) |
Year | 2016 |
Country | United States |
Company sponsor | University of Pennsylvania |
Other ID(s) | UPCC 11916, 825376 |
Vector information | |||||
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Cohort 1 | |||||||||||
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