Gene symbol | CD80 | Synonyms | B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7 | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3q13.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | CD80 molecule |
Gene symbol | CD86 | Synonyms | B7-2, B7.2, B70, CD28LG2, LAB72 | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3q13.33 | dbXrefs | |
Description | CD86 molecule |
Gene symbol | CD274 | Synonyms | B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, hPD-L1 | Type of gene | protein-coding |
Chromosome | 9 | Map location | 9p24.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD274 molecule |
GTO ID | GTC1696 |
Trial ID | NCT03060343 |
Disease | Lung Non-Small Cell Carcinoma |
Altered gene | PD-L1|CD80|CD86 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | PD-L1/CD80/CD86 CAR-T cells |
Phase | Early_Phase1 |
Recruitment status | Unknown |
Title | Zeushield Cytotoxic T Lymphocytes (Z-CTLs) for Relapsed or Refractory Non Small Cell Lung Cancer (NSCLC) |
Year | 2017 |
Country | China |
Company sponsor | Yu Fenglei |
Other ID(s) | Z-NSCLC-01 |
Cohort 1 | |||||||||||
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