Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC1694
Trial ID NCT03050190
Disease B-Cell Malignancy
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
Generation4th
PhasePhase1|Phase2
Recruitment statusUnknown
TitleA Phase I/II Multiple Center Trial of 4SCAR19 Cells in the Treatment of Relapsed and Refractory B Cell Malignancies
Year2013
CountryChina
Company sponsorShenzhen Geno-Immune Medical Institute
Other ID(s)GIMI-IRB-16001
Vector information
Vectorlentivirus
ConstructscFv-CD28-CD27-CD3ζ
Additional featureiCasp9

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 200
Age Child, Adult, Older_Adult
Lymph depletion Yes
References PMID: 30444200

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