Basic Information

Gene symbol CTAG1B Synonyms CTAG, ESO1, CT6.1, CTAG1, LAGE-2, LAGE2B, NY-ESO-1 Type of gene protein-coding
Description cancer/testis antigen 1B

GTO ID GTC1684
Trial ID NCT03017131
Disease Peritoneal Carcinoma | Fallopian Tube Carcinoma | Ovarian Carcinoma
Altered gene NY-ESO-1
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment NY-ESO-1 TCR-T cells
HLAHLA-A*02:01
PhasePhase1
Recruitment statusActive, Not Recruiting
TitleA Phase I Open Label Clinical Trial Evaluating the Safety and Efficacy of Adoptive Transfer of NY-ESO-1 TCR Engineered Autologous T Cells in Combination With Decitabine in Patients With Recurrent or Treatment Refractory Ovarian Cancer
Year2016
CountryUnited States
Company sponsorRoswell Park Cancer Institute
Other ID(s)i 283616|NCI-2016-01477|i 283616|P30CA016056|P50CA159981

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Age Adult, Older_Adult
Lymph depletion Yes

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