Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC1683
Trial ID NCT03016377
Disease Acute Lymphoblastic Leukemia | Immune System Disease
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
Co-treatment Rimiducid
Generation2nd
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleAdministration of Autologous CAR-T CD19 Antigen With Inducible Safety Switch in Patients With Relapsed/Refractory ALL
Year2018
CountryUnited States
Company sponsorUNC Lineberger Comprehensive Cancer Center
Other ID(s)LCCC 1541-ATL

Clinical Result

Cohort 1
Administration route infusion
Dosage 1E5 cells/kg, 5E5 cells/kg, 1E6 cells/kg
Donor type Autologous
Pts 54
Age Child, Adult, Older_Adult
Lymph depletion Yes
References PMID: 33624095

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