Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC1681
Trial ID NCT02992834
Disease B-Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
Generation2nd
PhasePhase4
Recruitment statusUnknown
TitleAnti-CD19:TCRζ Chimeric Antigen Receptor-T Cells in the Treatment for CD19+ B Cell Lymphoma
Year2016
CountryChina
Company sponsorThe First People's Hospital of Changzhou
Other ID(s)CAAA

Clinical Result

Cohort1: IL-2
Administration route None
Dosage 1E6 cells/kg
Donor type Allogeneic
Age Adult, Older_Adult
Lymph depletion Yes
Cohort2: IL-7/IL-15
Administration route None
Dosage 1E6 cells/kg
Donor type Allogeneic
Age Adult, Older_Adult
Lymph depletion Yes

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