Basic Information

Gene symbol CEACAM5 Synonyms CD66e, CEA Type of gene protein-coding
Description CEA cell adhesion molecule 5

Gene symbol GPC3 Synonyms DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 Type of gene protein-coding
Description glypican 3


GTO ID GTC1670
Trial ID NCT02959151
Disease Hepatocellular Carcinoma | Pancreatic Cancer | Colorectal Cancer
Altered gene GPC3|MESO|CEA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment GPC3/Mesothelin/CEA CAR-T cells
PhasePhase1|Phase2
Recruitment statusUnknown
TitleA Study of Chimeric Antigen Receptor T Cells Combined With Interventional Therapy in Advanced Liver Malignancy
Year2016
CountryChina
Company sponsorShanghai GeneChem Co., Ltd.
Other ID(s)CAR-T for liver cancer
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route intratumoral injection|vascular interventional therapy
Dosage 1.25~4E7 cells/cm3
Pts 20
Age Adult, Older_Adult

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