Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC1657
Trial ID NCT02935543
Disease Acute Lymphoblastic Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
Generation2nd
PhasePhase2
Recruitment statusTerminated
TitleCART19 in Adult Patients With Minimal Residual Disease During Upfront Treatment for ALL
Year2016
CountryUnited States
Company sponsorUniversity of Pennsylvania
Other ID(s)UPCC39416, 825668
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1~5E8 cells, Day1 10%, Day2 30%, Day3 60%
Donor type Autologous
Pts 1
Age Adult, Older_Adult

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