Basic Information

Gene symbol GPC3 Synonyms DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 Type of gene protein-coding
Description glypican 3

GTO ID GTC1641
Trial ID NCT02876978
Disease Lung Squamous Cell Carcinoma
Altered gene GPC3
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CAR-GPC3 T cells
PhasePhase1
Recruitment statusUnknown
TitleAnti-GPC3 CAR T for Recurrent or Refractory Lung Squamous Cell Carcinoma
Year2016
CountryChina
Company sponsorCARsgen Therapeutics Co., Ltd.
Other ID(s)CG1003
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E5~2E9 cells/kg
Donor type Autologous
Pts 20
Age Adult, Older_Adult
Lymph depletion Yes

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