| Gene symbol | TYR | Synonyms | ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 | Type of gene | protein-coding | |
| Chromosome | 11 | Map location | 11q14.3 | dbXrefs | Entrez:7299 MIM:606933 HGNC:HGNC:12442 Ensembl:ENSG00000077498 AllianceGenome:HGNC:12442 | |
| Gene perturbation-related omics dataset | PerturbAtlas | |||||
| Description | tyrosinase | |||||
| GTO ID | GTC1638 |
| Trial ID | NCT02870244 |
| Disease | Melanoma |
| Altered gene | TYR |
| Therapeutic/Target gene | Target gene |
| Therapy | TCR-T cell |
| Treatment | TIL 1383I TCR-T cells |
| HLA | HLA-A*02:01 |
| Phase | Phase1 |
| Recruitment status | Recruiting |
| Title | Adoptive T Cell Immunotherapy for Advanced Melanoma Using Engineered Lymphocytes: A Phase 1b Study |
| Year | 2016 |
| Country | United States |
| Company sponsor | Loyola University |
| Other ID(s) | 203729 |
| Cohort1: dose level 1 | |||||||||||
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| Cohort2: dose level 2 | |||||||||||
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| Cohort3: dose level 3 | |||||||||||
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