Basic Information

Gene symbol PDCD1 Synonyms CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description programmed cell death 1

GTO ID GTC1631
Trial ID NCT02862028
Disease Advanced Solid Tumor
Altered gene PD1
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment PD1 CAR-T cells
Co-treatment physiological saline|0.25% human alloalbumin
PhasePhase1|Phase2
Recruitment statusUnknown
TitlePD-1 Antibody Expressing CAR-T Cells for EGFR Family Member Positive Advanced Solid Tumor (Lung, Liver and Stomach)
Year2016
CountryChina
Company sponsorShanghai International Medical Center
Other ID(s)SIMC-20160101/02/03

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1~5E7 cells/kg in 300ml 2 cycles, each cycle one infusion on day 21, 43
Pts 20
Age Adult, Older_Adult

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