Basic Information

Gene symbol MUC1 Synonyms ADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description mucin 1, cell surface associated

GTO ID GTC1626
Trial ID NCT02839954
Disease Brain Glioma | Stomach Cancer | Pancreatic Carcinoma | Lung Non-Small Cell Carcinoma | Triple-Receptor Negative Breast Cancer | Hepatocellular Carcinoma | Colorectal Carcinoma
Altered gene MUC1
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment MUC1 CAR-NK cells
PhasePhase1|Phase2
Recruitment statusUnknown
TitleCAR-pNK Cell Immunotherapy in MUC1 Positive Relapsed or Refractory Solid Tumor
Year2016
CountryChina
Company sponsorPersonGen BioTherapeutics (Suzhou) Co., Ltd.

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 10
Age Adult, Older_Adult
Lymph depletion Yes

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