Basic Information

Gene symbol CD70 Synonyms CD27-L, CD27L, CD27LG, LPFS3, TNFSF7, TNLG8A Type of gene protein-coding
Description CD70 molecule

GTO ID GTC1624
Trial ID NCT02830724
Disease Breast Cancer | Melanoma | Renal Carcinoma | Ovarian Cancer | Pancreatic Cancer
Altered gene CD70
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD70 CAR-T cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleAdministering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers
Year2017
CountryUnited States
Company sponsorNational Cancer Institute (NCI)
Other ID(s)160131|16-C-0131
Vector information
Vectorretrovirus

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 124
Age Adult, Older_Adult
Lymph depletion Yes

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